Skip to main content
. 2012 Apr 4;32(8):1559–1566. doi: 10.1038/jcbfm.2012.47

Figure 2.

Figure 2

NBD-CSA transport in brain and spinal cord capillaries from wild-type (WT) and P-glycoprotein (P-GP)-null mice. Capillaries were incubated for 60 minutes in medium with 2 μmol/L NBD-CSA without (control) or with 5 μmol/L PSC833 and then imaged to measure luminal fluorescence. Each bar represents the mean value for 8 to 10 capillaries from a single preparation (pooled tissue from 10 rats or mice); variability is shown as standard error bars. Statistical comparisons: ***significantly different from control, P<0.001. NBD-CSA, [N-ɛ(4-nitrobenzofurazan-7-yl)-D-Lys8]-cyclosporine A.