Table 2.
Gene symbol | Vector | Lpcat1 shRNA | Lpcat1 overexpression |
IL-1β | 2.29 | 119.70 | -29.79 |
IL1RN | -1344.87 | 8.22 | -8579.43 |
IL4 | -3029.24 | -2.65 | 1.86 |
IL4R | 5.79 | 1.17 | -7.18 |
IL6 | 7.38 | 10.88 | 998.30 |
IL13 | -19.56 | -4.02 | 1237.60 |
IL13Ra1 | -171.65 | 65.34 | -544.96 |
IL13Ra2 | -2845.00 | 53.32 | 207.94 |
IL33 | 20.48 | 1.38 | -1.46 |
Autotaxin | 17.47 | 4.17 | -3.50 |
sST2 | -4.11 | 1667.34 | 21.91 |
ST2L | 2.42 | 138.14 | 781.44 |
TGF-b1 | -1.07 | -6.35 | -14.69 |
COX2 | 13.33 | 2.40 | 8.0 |
MMP2 | -13.55 | 443.67 | -565.48 |
MMP9 | 7.00 | 124.79 | -1.99 |
EDG1 | -93.05 | 541.37 | -1231.90 |
EDG2 | -6.85 | -1.26 | -48.50 |
EDG3 | 2.07 | 30.06 | -3.70 |
EDG4 | -1.27 | 83.48 | -36.25 |
EDG5 | -1.59 | 50.21 | -198.09 |
EDG6 | -70.20 | -1.56 | -343.30 |
EDG7 | -180.60 | -1978.24 | 2189.93 |
EDG8 | -441.62 | -2.52 | 19.79 |
CCT | -17.71 | -227.54 | 6397.68 |
CCTN | -1.49 | 1.10 | -22.63 |
SPL1 | 5.62 | 7.11 | 186.54 |
SGPP1 | -2.80 | -2.30 | -64.73 |
SGPP2 | -26.85 | 67.18 | 305.14 |
SGPL1 | -1.56 | -1.17 | -65.04 |
SPHK1 | -8.28 | 22.37 | -133.74 |
SPHK2 | 1.59 | -2.63 | 1223.39 |
LPA4 | -21.96 | 15.63 | -110.15 |
LPA5 | 1.15 | 275.01 | 3590.58 |
MET | 1.72 | -8.00 | -38.49 |
E-CADHERIN | -2.62 | -18.77 | -155.41 |
L19 | - 667.15 | 6.09 | -2752.77 |
LPCAT1 | 3.04 | -5.24 | 132.21 |
Gene expression fold changes were adjusted by baseline expression of each gene in the untreated normal cells.