Fig. 1.
Overall structure of the Hsp47:CMP complex. Hsp47 is shown in cartoon representation, and the CMP chains are depicted as sticks. α-Helices are drawn in gray. β-Sheet A is shown in orange, sheet B in magenta, and sheet C in violet. The segment corresponding to the RCL of inhibitory serpins is drawn in red. Asp385 is shown as sticks. The leading strand of the collagen triple helix is drawn in yellow, the middle strand in blue, and the trailing strand in green.