Table 5. Network gene modules most enriched with the inflammatome signature.

Cohort	Tissue	Gender	Module	Network size	Signature size	Signature in network	Module size	Signature in module	Fold enrichment	Enrichment P-value
BxH ApoE−/−	Adipose	Female	Blue	21 936	2505	2258	1991	672	3.2789252	1.13E−203
BxH ApoE−/−	Adipose	Male	Brown	21 936	2505	2258	1604	597	3.6157922	2.58E−203
BxH ApoE−/−	Muscle	Male	Blue	21 836	2505	2249	2803	721	2.4974442	1.16E−143
BxH ApoE−/−	Liver	Female	Red	21 936	2505	2258	605	291	4.6727346	2.81E−129
BxH ApoE−/−	Liver	Male	Yellow	21 936	2505	2258	1206	395	3.1818763	1.29E−108
BxH ApoE−/−	Muscle	Female	Turquoise	21 842	2505	2250	4518	858	1.8435331	4.40E−91
NKI	Breast (cancer)	All	Purple	19 570	2276	1995	387	130	3.2951888	2.56E−37
NKI	Breast (cancer)	All	Black	19 570	2276	1995	644	201	3.0616681	1.97E−51
HCC	Liver (cancer)	All	Turquoise	14 878	2276	1835	2405	510	1.7193472	2.47E−42
IFA	Adipose	Male	Turquoise	5580	2276	824	1123	316	1.90552352	1.50E−40
IFA	Adipose	Female	Turquoise	5561	2276	842	1696	411	1.6005041	2.10E−34
HLC	Liver	All	Yellow	4408	2276	623	180	84	3.3018727	7.63E−28