Table 7.
IN | TP |
T0 |
T3 |
T6 |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Clin | IFAT | LN-CE | BC n-PCR | CS n-PCR | Clin | IFAT | LN-CE | BC n-PCR | CS n-PCR | Clin | IFAT | LN-CE | BC n-PCR | CS n-PCR | ||
1 | M+A | P | 1:640 | + | + | + | A | 1:320 | + | − | − | A | 1:640 | + | + | + |
2 | M+A | P | 1:640 | + | + | + | A | 1:160 | − | − | − | A | 1:160 | − | + | + |
3 | M+A | P | 1:640 | + | + | + | A | 1:320 | − | − | − | A | 1:160 | − | + | + |
4 | M+A | P | 1:1280 | + | − | + | A | 1:160 | − | − | − | A | 1:80 | − | − | − |
5 | M+A | P | 1:160 | + | − | + | A | 1:160 | − | − | − | A | 1:160 | − | − | + |
6 | M+A | P | 1:1280 | + | + | + | A | 1:320 | − | − | − | A | 1:160 | − | − | + |
7 | M+A | P | 1:2560 | + | + | + | A | 1:320 | − | + | − | A | 1:320 | + | + | + |
8 | M+A | P | 1:640 | + | − | + | A | 1:160 | − | − | − | A | 1:160 | + | + | − |
9 | M+A | P | 1:320 | + | − | + | A | 1:80 | − | − | − | A | 1:160 | − | − | + |
10 | M+A | P | 1:640 | − | − | + | A | 1:160 | − | − | − | A | 1:160 | − | − | + |
11 | M+A | P | 1:640 | + | + | + | A | 1:160 | − | − | + | ND | ND | ND | ND | ND |
12 | M+A | P | 1:320 | + | + | + | A | 1:160 | − | − | + | ND | ND | ND | ND | ND |
13 | MA+A | P | 1:1280 | + | − | + | A | 1:320 | − | − | + | A | 1:160 | − | − | + |
14 | MA+A | P | 1:320 | − | + | + | A | 1:160 | − | − | + | A | 1:160 | − | − | + |
15 | MA+A | P | 1:320 | + | − | + | A | 1:160 | − | − | + | A | 1:160 | − | − | + |
16 | MA+A | P | 1:160 | + | − | + | A | 1:80 | − | − | + | A | 1:80 | − | − | + |
17 | MA+A | P | 1:320 | + | − | + | A | 1:160 | − | − | − | A | 1:160 | − | + | + |
18 | MA+A | P | 1:640 | − | − | + | A | 1:320 | − | − | − | A | 1:160 | − | + | + |
19 | MA+A | P | 1:640 | + | − | + | A | 1:320 | + | − | − | A | 1:640 | + | + | + |
20 | MA+A | P | 1:1280 | + | + | + | A | 1:160 | − | − | − | A | 1:160 | − | − | + |
IN, identification number; TP, treatment protocol; T0, before treatment; T3, 3 months from treatment onset; T6, 6 months from treatment onset; Clin, clinical signs; IFAT, indirect immunofluorescence antibody test; LN-CE, lymph node cytological examination; BC n-PCR, n-PCR on buffy coat; CS n-PCR, n-PCR on conjunctival swab; M+A, miltefosine plus allopurinol; MA+A, meglumine antimoniate plus allopurinol; A, absence; P, presence; ND, not done (dog lost to follow-up).