Table 6.
Adverse event | No. (%) of subjects |
|||
---|---|---|---|---|
Lersivirine at 1,000 mg q.d. + rifampin at 600 mg q.d. (n = 15) |
Lersivirine at 1,000 mg q.d. + placebo q.d. (n = 16) |
|||
Mild | Moderate | Mild | Moderate | |
Chromaturia | 15 (100) | 0 | 0 | 0 |
Dizziness | 8 (53) | 0 | 7 (44) | 1 (6) |
Nausea | 2 (13) | 1 (7) | 7 (44) | 0 |
Somnolence | 1 (7) | 0 | 2 (13) | 0 |
Insomnia | 2 (13) | 0 | 1 (6) | 0 |
Flatulence | 0 | 0 | 3 (19) | 0 |
Headache | 1 (8) | 0 | 1 (6) | 1 (6) |
Abdominal distension | 0 | 0 | 2 (13) | 0 |
Diarrhea | 2 (13) | 0 | 1 (6) | 0 |
Lip dry | 0 | 0 | 2 (12) | 0 |
No cases of severe treatment-emergent adverse events were recorded.