Table 1.

LS mean concentrations of tulathromycin in plasma from mice treated with a single s.c. injection of tulathromycin at 7 and 28 mg/kg body weight

Time point	Group	Tulathromycin (ng/ml)
		LS meana	95% CIa
30 min	T-28	11,700	490–18,500
	T-7-LPS	6,790	184–11,700
	T-7-LPS-CP	6,700	1,230–12,200
	T-7	3,280	1,500–5,070
1 h	T-28	792	214–1,370
	T-7-LPS	3,870	713–7,030
	T-7-LPS-CP	6,920	1,870–12,000
	T-7	2,060	378–3,700
24 h	T-28	145	26.7–260
	T-7-LPS	50.8	13.7–87.9
	T-7-LPS-CP	59.1	11.0–107
	T-7	103	28.1–180
48 h	T-28	100	27.2–174
	T-7-LPS	51.1	13.8–88.4
	T-7-LPS-CP	57.0	15.4–98.6
	T-7	60.0	16.2–103
72 h	T-28	109	20.2–199
	T-7-LPS	19.2	5.20–33.2
	T-7-LPS-CP	5.32	0.31–10.3
	T-7	24.4	4.50–44.2
96 h	T-28	26.2	7.10–45.4
	T-7-LPS	16.9	4.60–29.3
	T-7-LPS-CP	15.9	2.93–28.9
	T-7	9.28	2.50–16.0
120 h	T-28	19.2	3.50–34.9
	T-o7-LPS	10.9	2.00–19.9
	T-7-LPS-CP	6.89	1.27–12.5
	T-7	10.8	2.90–18.7
144 h	T-28	13.6	3.70–23.5
	T-7-LPS	7.82	0.50–15.2
	T-7-LPS-CP	6.48	1.75–11.2
	T-7	15.4	4.20–26.7

^aBack-transformed.