Table 2.

LS mean concentrations of tulathromycin in lung tissue homogenates from mice treated with a single s.c. injection of tulathromycin at 7 and 28 mg/kg body weight

Time point	Group	Tulathromycin (ng/ml)
		LS meana	95% CIa
30 min	T-28	15,700	4,550–2,600
	T-7-LPS	3,940	1,440–6,430
	T-7-LPS-CP	5,240	1,910–8,560
	T-7	4,410	2,198–6,621
1 h	T-28	27,900	5,050–50,500
	T-7-LPS	3,250	1,192–5,320
	T-7-LPS-CP	5,500	2,010–8,980
	T-7	3,150	1,150–5,140
24 h	T-28	1,760	643–2,870
	T-7-LPS	1,170	213–2,140
	T-7-LPS-CP	1,680	614–2,740
	T-7	1,170	426–1,910
48 h	T-28	4,770	1,740–7,790
	T-7-LPS	1,050	305–1,800
	T-7-LPS-CP	1,000	292–1,720
	T-7	2,070	603–3,540
72 h	T-28	4,800	1,400–8,210
	T-7-LPS	889	325–1,450
	T-7-LPS-CP	680	123–1,240
	T-7	1,950	715–3,196
96 h	T-28	4,760	1,380–8,130
	T-7-LPS	824	301–1,350
	T-7-LPS-CP	879	159–1,600
	T-7	1,690	619–2,770
120 h	T-28	4,240	1,550–6,940
	T-7-LPS	516	189–844
	T-7-LPS-CP	926	338–1,510
	T-7	1,230	359–2,110
144 h	T-28	3,860	1,120–6,590
	T-7-LPS	1,060	308–1,810
	T-7-LPS-CP	750	218–1,280
	T-7	1,020	375–1,670

^aBack-transformed.