Fig 2.
Deduced amino acid sequences aligned to HIV-1HXB2 Env region C3. gp120 C3 amino acids 329 to 393 for HIV-1 and 338 to 407 for HIV-2 are shown using HIV-1HXB2 and HIV-2ROD as the reference sequences, respectively. Colons depict the same amino acid as in the HIV-1 reference sequence. Brackets signify region not present in HIV-1 but present in HIV-2. CRF01_AE HIV-1 H375 and the corresponding HIV-2 W390 are highlighted in red. Sequences represent clones or the dominant viral variant of primary patient HIV isolate quasispecies used in this study. Sensitivity (S) and resistance (R) to BMS-599793, VRC03, and b12 are indicated. ND, not done.