Table 1.
MICs of LFF571 against C. difficile strains used in the studya
| Strain | Description | LFF571 MIC (μg/ml) |
|---|---|---|
| NB95002 | Clinical isolateb | 0.125 |
| NB95013 | ATCC 43255 | 0.5 |
| NB95026 | Clinical isolate (MOH838)c | 0.5 |
| NB95031 | Clinical isolate (MOH082, REA type AA)c | 0.5 |
| NB95047 | Clinical isolate (MOH108, REA type J)c | 0.25 |
a
MICs were determined by agar dilution methods according to Clinical and Laboratory Standards Institute (CLSI) guidelines (5). REA, restriction endonuclease analysis.
b
Novartis collection.
c
Kindly provided by Donald Low at Mount Sinai Hospital, Toronto, Canada.