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Growth competition experiments. The parental 43c strain of HAV and the G1217D mutant were inoculated into rats in the absence (A and C) or presence (B and D) of the H7C27 MAb, to which the G1217D mutant is resistant. The 43c/G1217D mutant ratios tested were 1:1 (A and B) and 1:9 (C and D). The mean proportion of each virus in serum was determined at different times p.i. (at 21 days p.i. for the liver).
