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Expression of PARP12L affects replication of VEEV encoding wt capsid protein. (A) Schematic representation of recombinant VEEV genomes encoding wt capsid protein and the PARP12L genes in direct or reverse orientations. (B) Analysis of replication of the recombinant viruses in BHK-21 and NIH 3T3 cells. Media were harvested at different times postinfection, and virus titers were determined by plaque assay on BHK-21 cells.
