Fig 2.

SHIV_AD8 induces sustained plasma viremia and loss of CD4⁺ T cells in intravenously inoculated rhesus macaques. The levels of plasma viremia (A); absolute numbers of peripheral CD4⁺ T cells (B), memory CD4⁺ T cells (C), and naïve CD4⁺ T cells (D); and percentages of BAL fluid CD4⁺ T cells (E) are shown. Note that purple symbols denote animals infected with SHIV_AD8-CE8J, maroon symbols denote animals infected with SHIV_AD8-CL98, and orange symbols denote animals infected with SHIV_AD8-CK15. Macaques euthanized with AIDS are indicated (†).