Table 3.
Association between HRM score and sequence-based diversity measuresa
| Region | Diversity measure | Slope (95% CI) | P value | R2 |
|---|---|---|---|---|
| GAG | % diversity | 0.19 (0.15, 0.23) | <0.001 | 0.23 |
| % complexityb | 0.10 (0.07, 0.13) | <0.001 | 0.05 | |
| Shannon entropy | 0.05 (0.04, 0.06) | <0.001 | 0.22 | |
| ENV | % diversityc | 0.51 (0.41, 0.60) | <0.001 | 0.34 |
| % complexity | 0.25 (0.18, 0.32) | <0.001 | 0.14 | |
| Shannon entropy | 0.06 (0.05, 0.06) | <0.001 | 0.40 |
a
Results of a linear mixed model using the HRM score to predict sequence-based diversity measures.
b
Two extreme values were removed for the first time point (seroconversion). One of the excluded values was from an individual who had dual infection at seroconversion (see Materials and Methods).
c
Three extreme values were removed for the first time point. All of these values were collected from individuals with dual infection (see Materials and Methods).