Table 3.

Impact of resistance mechanisms on the in vitro susceptibility of C. albicans to voriconazole and posaconazole^a

Strain	Resistance mechanism(s)		MIC (μg/ml)
	CDRb	ERG 11c	VRC	PSC
DSY294	Basal	WT/WT	0.007	0.03
DSY296	Increase	G464S/G464S	2	0.25
DSY3083	Basal	G464S/G464S	0.12	0.03
DSY3604	Basal	G464S/WT	0.06	0.03
DSY3606	Increase	WT/WT	0.12	0.25

^aData compiled from reference 41. VRC, voriconazole; PSC, posaconazole; WT, wild type.

^bData represent the level of expression of CDR1/CDR2 efflux pumps.

^cData represent wild type or a mutation (G464S) in either or both of two ERG 11 alleles.