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Killing curve analysis of imipenem-M131 combinations. Cultures of MRSA COL were treated with M131 at 1 μg/ml (1× MIC) with or without imipenem (4 μg/ml; 0.25× MIC), and viable bacterial counts (CFU/ml) were monitored over 24 h. M131 was also tested alone at 8 μg/ml (8× MIC).
