Table 1.
Association of p53-72 Polymorphism with Clinical and Genetic Characteristics of Patients with NB.
| Feature | p53 Arg72Pro | ||
| Arg/Arg or Arg/Pro (%) | Pro/Pro (%) | P* | |
| Stage | .338 | ||
| 1–2–4 S | 98 (98.0) | 2 (2.0) | |
| 3–4 | 172 (95.0) | 9 (5.0) | |
| MYCN | .304 | ||
| Non amp | 205 (95.3) | 10 (4.7) | |
| Amp | 69 (98.6) | 1 (1.4) | |
| Age | .031 | ||
| <18 mo | 115 (99.1) | 1 (0.9) | |
| ≥18 mo | 158 (94.0) | 10 (6.0) | |
| Site | .523† | ||
| Extra adrenal | 139 (97.2) | 4 (2.8) | |
| Adrenal | 121 (95.3) | 6 (4.7) | |
| Multiple sites | 1 (100.0) | ||
Amp indicates amplified; non amp, non amplified.
*
P: two-tailed Fisher exact test.
†
P value was calculated by comparing tumors with adrenal and extra-adrenal localization only.