Table 1.

Phalloidin treatment partially rescues circulation defects in s434 mutants^a

Treatment	No. of embryos with:		Total no. of embryos treated
	Pericardial edema and no circulation	Pericardial edema and circulation
DMSO	46	0	203
Phalloidin (2 μM)	66	27	343

^aProgeny from a cross of actc1a^s434+/− carriers were treated with either 2 μM DMSO (control) or phalloidin-oleate from 24 hpf to 48 hpf and evaluated for pericardial edema and circulation. Our results show that none of the DMSO-treated embryos with pericardial edema had circulation at 48 hpf. However, of the phalloidin-treated embryos, 66 embryos showed pericardial edema with no circulation, and 27 embryos showed pericardial edema and circulation. The P value for a chi-square test was <0.0001, indicating statistical significance.