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Perinatal lethality in 4ehp knockout mice. (A) Summary of 4ehp heterozygous intercrosses. Genotyping of embryos and pups at indicated stages was performed by PCR. (B and C) Gross appearance of 4ehp WT and KO pups at postnatal day 0. The arrow indicates a 4ehp KO pup. (D) Body weight of 4ehp WT, heterozygous (HE), and KO pups at E18.5. All values represent means ± SD. n = 5 for each genotype.
