Table 5.
Summary of Incident Cases of HIV Infection
| Location | Treatment group | Baseline Ad5 titer | Number of doses received | Days postdose 3 first positive HIV test obtained | HIV RNA viral load at diagnosis (copies/ml) | Number of days post last negative HIV test |
|---|---|---|---|---|---|---|
| South America | HIV-1 gag MRKAd5 1 × 1010 | 46.7 | 3 | 183 | 648,003 | 69 |
| South America | HIV-1 gag MRKAd5 1 × 109 | 81.3 | 3 | 183 | >75,000a | 71 |
| South Africa | HIV-1 gag MRKAd5 1 × 109 | 340.4 | 3 | 538 | 34,724 | 153 |
| South Africa | HIV-1 gag MRKAd5 1 × 1010 | 480.6 | 3 | 548 | 10,266 | 365 |
a
At the time this HIV RNA sample was collected, an initial HIV rapid test (UNI-GOLD Recombigen HIV) was nonreactive, suggesting acute infection.