Table 3.
Outcomes stratified by pre-index medication possession ratio categories
| Pre-period MPR categories (%) | RP | non-RP | P valuea | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
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| Pre-period (n = 4633) | Post-period (n = 4633) | Pre-period (n = 4633) | Post-period (n = 4633) | ||||||||
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| n | Mean | SD | Mean | SD | n | Mean | SD | Mean | SD | ||
| MPR | |||||||||||
| 0–19 | 3 | 10.89 | (7.58) | 58.73 | (26.88) | 2 | 4.83 | (0.16) | 41.21 | (8.36) | 0.6105 |
| 20–39 | 144 | 30.76 | (5.52) | 62.24* | (21.07) | 153 | 34.29 | (4.06) | 57.32* | (19.66) | 0.0008 |
| 40–59 | 466 | 50.20 | (5.18) | 66.31* | (20.66) | 584 | 50.28 | (5.29) | 60.84* | (20.46) | 0.0001 |
| 60–79 | 1098 | 70.92 | (5.32) | 76.18* | (18.93) | 905 | 70.23 | (5.83) | 66.12* | (20.15) | 0.0001 |
| 80–100 | 2922 | 94.51 | (5.98) | 83.95* | (16.18) | 2989 | 95.15 | (5.90) | 78.65* | (19.74) | 0.0001 |
| Refill timing (days) | |||||||||||
| 0–19 | 3 | 93.67 | (29.57) | 27.37 | (21.82) | 2 | 88.00 | (16.97) | 43.33 | (15.08) | 0.6118 |
| 20–39 | 144 | 67.76 | (19.56) | 24.52* | (24.52) | 153 | 56.25 | (11.84) | 0.12* | (23.10) | 0.0001 |
| 40–59 | 466 | 29.33 | (6.56) | 20.40* | (21.57) | 584 | 29.08 | (6.69) | 25.17* | (22.75) | 0.0004 |
| 60–79 | 1098 | 11.69 | (3.40) | 12.48 | (17.42) | 905 | 12.32 | (4.22) | 20.31* | (20.71) | 0.0001 |
| 80–100 | 2922 | 1.40 | (2.00) | 7.35* | (13.36) | 2989 | 1.36 | (2.06) | 11.61* | (17.73) | 0.0001 |
Notes:
*
P < 0.05 versus pre-period values (paired t-test).
a
Statistical test: unpaired t-test for pre-post difference scores.
Abbreviations: MPR, medication possession ratio; non-RP, without reminder packaging; RP, reminder packaging; SD, standard deviation.