Table 3. Univariate and multivariate models for baseline characteristics.

				Univariate analysis using chi-square test			Multivariate analysis using logistic regression
Parameter		Patients = 167 (%)	Control = 162 (%)	p-value	OR	95%CI	Adjusted p-value	OR	95%CI
Age (Median)	>63	78 (47%)	1 (0.6%)	<0.001	141	19–1030
	≤63	89(53%)	161(99.4%)
Gender	Male	129(77%)	100(62%)	0.002	2.105	1.30–3.40	0.134	1.615	0.86–3.02
	Female	38(23%)	62(38%)
Smoking	Currentsmoker/ex-smoker	112(67%)	66(41%)	<0.001	2.962	1.89–4.64	<0.001	3.385	1.86–6.15
	Neversmoker	55(33%)	96(59%)
19TG	TG,GG	111(66%)	50 (31%)	<0.001	4.440	2.79–7.05	0.436	1.331	0.64–2.73
	TT	56(34%)	112(69%)
105CT	CT,TT	24(14%)	47 (29%)	0.001	0.411	0.23–0.71	0.169	0.602	0.29–1.24
	CC	143(86%)	115 (71%)
541AG	AG,GG	116(69%)	30(19%)	<0.001	10.008	5.97–16.75	0.015	3.582	1.27–10.04
	AA	51(31%)	132(81%)
552AC	AC,CC	125(75%)	33(20%)	<0.001	11.634	6.93–19.53	0.001	5.364	1.92–14.96
	AA	42(25%)	129(80%)
IVS1+130	GT,TT	45(27%)	85(52%)	<0.001	0.334	0.21–0.52	<0.001	0.191	0.09–0.36
	GG	122(73%)	77(48%)