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. 2012 Aug 17;7(8):e43481. doi: 10.1371/journal.pone.0043481

Table 1. CD4+ T cell epitopes to virulent Salmonella.

Protein Epitopea Sequence Protein function ELISPOTb
AhpC 154–168 AAQYVAAHPGEVCPA alkyl hydroperoxide reductase subunit C 5.1
EutC 243–257 CYAVYSPRVATTVEA ethanolamine ammonia-lyase small subunit 2.4
STM1540 262–276 GVYYTTYAPQATSAH putative hydrolase 17.4
a

Indicated is the amino-acid position in Salmonella Typhimurium strain LT2 [28].

b

Mice were infected orally with 1×107 Salmonella Typhimurium (strain LT2). After 18 days, CD4+ T cells were tested in ELISPOT assays for IFN-γ production. Data is presented as Stimulation Index (SI), calculated as the number of spot forming cells after stimulation with peptide-loaded dendritic cells divided by spot forming cells in background.