Table 1. Acute muscle damage activates miRNA machinery in isolated myofibers.

	2d	5d	7d	10d
miR-206	−1,2	18,2	26,8**	4,5*
miR-31	1	19,5	14,2	9,6***
miR-21	2,7	5,5	12,7**	2,3*
miR-335-3p	1	3,1	8,9*	1,1
miR-27a	1,4	2,7	4,9**	1,7
miR-142-p	3,7*	6,5	8,6	1
miR-223	1	2,6**	1,4	−1,8
miR-15b	1,1	1,9	1,4	−1,7
miR-17	1,3	1,1	1,1	1,2
miR-128a	−2	−1,1	−1	−3
miR-221	−1,9	−2,8	−2	−2,8
miR-199a-5p	−2,7	1,3	2,2	−1,3
miR-199b	−1,3	1,1	1,4	1
miR199b*	1,1	−1,3	−1,2	−1,7

Dystrophic-fibres associated miRNAs were quantified by Q-PCR in single fibres isolated from TA of c57bl mice (n = 10) after CTX-injection. Mice were sacrified at the day 2, 5, 7, 10 after CTX-injury. In the table are represented the fold change values of tested miRNAs in CTX-injected muscle compare to controlateral not injected TA. MiR-206, miR-31, miR-21, miR-335-5p, miR-27a, miR-142-5p and miR-223 were significantly up-regulated afterwards muscle damage respect damaged muscle. Otherwise the other 7 miRNAs were not triggered upon CTX-injection.

(Two-tail parametric t-test; *p value <0, 05; **p value <0, 01; ***p value <0,001).