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A: % changes in muscle diameter showed a significant increase in ET-1 treated muscle (n = 11), but not in control group (n = 5) by pair’s t-test. Significantly increase in myocyte width (B) but not in myocyte length (C) confirmed hypertrophic effect of ET-1. Values are mean ± SEM from 3 muscles in each group. *P<0.05 vs. control by student t-test.
