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. 2012 Aug 17;7(8):e43179. doi: 10.1371/journal.pone.0043179

Figure 3. Effect of signaling inhibitors on developed force before and after ET-1 treatment.

Figure 3

No significant difference in developed force at start among group as well as 30 min later before inhibitors was added (A, B). After 30 min incubation with GF109203X, significant increase in developed force was observed (C). Significant increases in developed force by ET-1 after 24 hours treatment was observed by the inhibitors of NCX, MEK-1, CaMKII, NFAT-calcineurin association, PKC, and IP3 receptors (D). Values are mean ± SEM from 5–8 muscles in each group. *P<0.05 vs. control by ANOVA.