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. 2012 Aug 17;7(8):e43204. doi: 10.1371/journal.pone.0043204

Figure 4. miR-338-3p inhibits cell proliferation by Edu assay.

Figure 4

(A–B) Representative profiles of Edu cell proliferation after transfection with miR-338-3p mimics or inhibitor in LO2/HBx-d382 and LO2/HBx cells compared to their negative control transfection (magnification 100×). (C) Rate of Edu positive cells in S phase. Gain of miR-338-3p inhibits the cellular DNA replication in HBx-expressed LO2 cells and control cells, whereas loss of miR-338-3p expression demonstrates an adverse result, especially in LO2/HBx-d382 cells. (*P<0.001; **P<0.01; ***P<0.05).