Table 1. List of select WA-regulated genes in H2373 MPM cells.
ID | SYMBOL | Name | ENTREZ | FoldChange | Direction |
6380717 | HSPA1A | heat shock 70 kDa protein 1A | 3303 | 26.526557 | DOWN |
5670465 | ADM | adrenomedullin | 133 | 25.887796 | DOWN |
3850433 | HSPA1B | heat shock 70 kDa protein 1B | 3304 | 24.628061 | DOWN |
60079 | DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 3337 | 24.051914 | DOWN |
870379 | ZFAND2A | zinc finger, AN1-type domain 2A | 90637 | 15.772064 | DOWN |
1340600 | PPP1R15A | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 23645 | 11.242614 | DOWN |
6660601 | HMOX1 | heme oxygenase (decycling) 1 | 3162 | 8.7309379 | DOWN |
160092 | HSPA6 | heat shock 70 kDa protein 6 (HSP70B') | 3310 | 8.2488636 | DOWN |
830619 | DDIT3 | DNA-damage-inducible transcript 3 | 1649 | 7.4905684 | DOWN |
6860377 | DUSP1 | dual specificity phosphatase 1 | 1843 | 6.8823963 | DOWN |
4610189 | HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 9709 | 5.7754888 | DOWN |
5420095 | MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 4609 | 5.2859313 | DOWN |
150327 | HSPH1 | heat shock 105 kDa/110 kDa protein 1 | 10808 | 5.0773806 | DOWN |
4390450 | SGK1 | serum/glucocorticoid regulated kinase 1 | 6446 | 5.0676214 | DOWN |
4880673 | GADD45A | growth arrest and DNA-damage-inducible, alpha | 1647 | 4.8698733 | DOWN |
7570324 | ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3399 | 4.6867504 | DOWN |
870338 | EGR1 | early growth response 1 | 1958 | 4.3381067 | DOWN |
7160239 | FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 2354 | 4.2438425 | DOWN |
6510367 | JUN | jun oncogene | 3725 | 3.972581 | DOWN |
1710553 | HSPA6 | heat shock 70 kDa protein 6 (HSP70B') | 3310 | 3.6847097 | DOWN |
1340075 | BAG3 | BCL2-associated athanogene 3 | 9531 | 3.6837105 | DOWN |
4210524 | RND3 | Rho family GTPase 3 | 390 | 3.4998418 | DOWN |
730286 | TXNRD1 | thioredoxin reductase 1 | 7296 | 3.4690154 | UP |
1260086 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 3398 | 3.2341928 | DOWN |
4280017 | FOS | v-fos FBJ murine osteosarcoma viral oncogene homolog | 2353 | 3.1238524 | DOWN |
4920110 | GADD45B | growth arrest and DNA-damage-inducible, beta | 4616 | 3.0608382 | DOWN |
4860286 | UBB | ubiquitin B | 7314 | 2.7247999 | DOWN |
670386 | ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 3397 | 2.7209816 | DOWN |
7650358 | TGFBI | transforming growth factor, beta-induced, 68 kDa | 7045 | 2.3790355 | UP |
1170709 | CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 1000 | 2.3726027 | UP |
780270 | TIMP2 | TIMP metallopeptidase inhibitor 2 | 7077 | 2.2000615 | UP |
4040097 | KLF6 | Kruppel-like factor 6 | 1316 | 2.1886976 | DOWN |
3190148 | DDIT4 | DNA-damage-inducible transcript 4 | 54541 | 2.1817718 | DOWN |
830661 | DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 131566 | 2.1806644 | UP |
7050278 | RUNX1 | runt-related transcription factor 1 | 861 | 2.1623177 | DOWN |
3710544 | EIF1 | eukaryotic translation initiation factor 1 | 10209 | 2.1583103 | DOWN |
670086 | MXD1 | MAX dimerization protein 1 | 4084 | 2.1341046 | DOWN |
1470215 | MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 1326 | 2.1100298 | DOWN |
3060300 | UBC | ubiquitin C | 7316 | 2.0749465 | DOWN |
6660343 | RBM14 | RNA binding motif protein 14 | 10432 | 2.0674976 | DOWN |
Genes upregulated by WA are in bold.