Skip to main content
. 2012 Aug 17;7(8):e42127. doi: 10.1371/journal.pone.0042127

Figure 3. Pathway Scores for Cell Communication and Cell Adhesion Pathways and their Involvement in Trans-Epithelial Resistance (TER).

Figure 3

The set of genes within the gap junction, tight junction, adherens junction and integrin-mediated cell adhesion are contained in the cell communication pathway. (3a). Pathway scores for Adherens Junction (AJ), Cell Communication (CC), Gap Junction (GJ), Integrin-mediated Cell Adhesion (IMCA), Tight Junction (TJ) and Trefoil Factors Initiated Mucosal Healing (TFIMH). Red indicates an activated state while green indicates suppression. Note the reversal of the cell communication pathway from suppressed to activated from the Phase 1 (30–60 min.) to the Phase 3 time period (720 min.). (3b). Changes in the Trans-Epithelial Resistance of polarized T-84 cells exposed to MAP for 24 h. Data represent mean ± SD from 3 measurements at each time point and three independent experiments.