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. 2012 Aug 17;7(8):e42127. doi: 10.1371/journal.pone.0042127

Table 8. Key Down-Regulated Mechanistic Genes of the Trefoil Factors Initiated Mucosal Healing Pathway.

PTK2 protein tyrosine kinase 2 Encodes a cytoplasmic protein tyrosine kinase that is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases.
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29) Encodes the integrin beta 1 protein which is a membrane receptor involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells.
MAPK1 mitogen-activated protein kinase 1 Agene encoding a member of the MAP kinase family known as extracellular signal-regulated kinases (ERKs) which act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development
CTNNB1 catenin beta 1 Agene encoding a protein necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells and also anchors the actin cytoskeleton