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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Curr Opin Virol. 2012 Jun 5;2(4):419–425. doi: 10.1016/j.coviro.2012.05.003

Table 3.

Serum neutralizing antibody (SNA) seroresponse rates and vaccine efficacy (Prot) against severe RVGE in selected RV5 studies.

Strain Serotype Bangladesh and Vietnam OPV [27] Ghana, Kenya and Mali OPV [28] Latin America OPV [30] US and Finland No OPV [5]
% SNA % Prot % SNA % Prot % SNA % Prot % SNA % Prot
G1 32.1 46.2 18.5 32.3 59.9 NR 76 74.9*
G2 9.9 29.2 9 27.1 36.3 NR 34.3 63.4*
G3 28.2 67 6.3 62.3 29.3 NR 22.1 82.7*
G4 18.3 NR 26.5 NR 50.9 NR 54.1 48.1*
P1A [8] 27.5 49.7 14.4 36.1 43.9 NR 53.7 NR
*

Clinical efficacy calculated for RVGE of any severity.

NR = not reported.