Table 4.
Logistic regression analysis of Amnisure & Fibronectin tests in predicting Intra-amniotic Infection and/or Inflammation and Spontaneous Preterm Birth in patients with preterm labor and intact membranes
| Test Result | Intra-amniotic infection and/or inflammation (n=27) | Spontaneous Preterm Delivery | ||||||
|---|---|---|---|---|---|---|---|---|
| < 35 weeks a (n=34) | < 37 weeks b (n=46) | |||||||
| OR | CI | OR | CI | OR | CI | |||
| Amnisure Test (n=90) | (+) | 3.9 | 1.01–15.1 | 2.7 | 0.7–10.3 | 3.6 | 0.6–20.6 | |
| (−) | 1 | 1 | 1 | |||||
| Fibronectin Test (n=64) | (+) | 8.5 | 1.6–46.9 | 7.3 | 1.8–29.5 | 9.8 | 2.2–43.5 | |
| (−) | 1 | 1 | 1 | |||||
| Fibronectin (+) (n=28) | Aminsure Test | (+) | 0.5 | 0.06–5.3 | 0.4 | 0.1–2.2 | 2.3 | 0.2–28.1 |
| (−) | 1 | 1 | 1 | |||||
| Fibronectin (−) (n=36) | Aminsure Test | (+) | 25.2 | 1.7–363.8 | 66.7 | 2.8->999 | 10.7 | 0.97–117.9 |
| (−) | 1 | 1 | 1 | |||||
Note: All models adjusted for gestational length at time of test and cervical dilatation except those stratified by fibronectin result due to sample size restrictions;
Four patients who delivered preterm before (before 35 weeks) by augmentation of labor or cesarean delivery due to maternal- fetal indications were excluded from this analysis;
Nine patients who delivered preterm before 37 weeks by augmentation of labor or cesarean delivery due to maternal- fetal indications were excluded from this analysis.