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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: J Trauma Acute Care Surg. 2012 Aug;73(2):408–412. doi: 10.1097/TA.0b013e31825a789b

Figure 1.

Figure 1

Nitrite (NO −2) production of hepatocytes simultaneously treated with rhIL-1β, rrIFN-□, and different concentrations of E2 in serum-containing medium. Results are the mean + SEM of 3 independent rat experiments performed separately in which NO −2 was measured from supernatant of hepatocytes cultured in triplicates for each rat experiment. (A) NO −2 measured from cells stimulated with the cytokines alone minus E2 (3rd column from Y-axis) was used as positive control and all other treatments expressed as a percentage of the control. Asterisk represents a significant (p < 0.05) difference from control cells. (B) Western blot analysis of iNOS protein. A dose-dependent suppression of cytokine-stimulated iNOS protein expression by E2 is demonstrated.