Table.

Target proteins	Effect on activity	Signaling pathways	References
Ryanodine receptors	increase	Ca2+	[105] [106]
eNOS	inhibition	NO signaling	[89]
Na+-K+ ATPase	inhibition	voltage dependend signaling	[107]
p21Ras	increase	p21Ras-MEK-ERK	Clavereul et al [108]
p50	inhibition	NF-κB signaling	[77]
RelA/p65	inhibition	NF-κB signaling	[72]
IKKβ	inhibition	NF-κB signaling	[78]
TRAF 6	inhibition	NF-κB signaling	[79]
c-Jun	inhibition	AP-1 signaling	[109]
GAPDH	inhibition	Ca2+signaling	[110]
p53	inhibition	p53 signaling	[111]
Adenosine transporter (ANT)	varies	mitochondrial function	[90]
Ubiquitin ligases E 1,E2	inhibition	protein degradation	[112]
Rpn2 (regulator of 26 proteosome)	inhibition	protein degradation	[113]
Fas	increase	apoptosis	[114]
caspase 3	inhibition	apoptosis	[115]
PTP1B	inhibition	various signaling pathways	[116]