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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: J Neural Eng. 2011 Nov 4;8(6):065003. doi: 10.1088/1741-2560/8/6/065003

Figure 6.

Figure 6

Frame by frame depiction of the In escape mechanism when feedback is present in the model. In the top boxes RG - F and RG - E positions are plotted at various timepoints on their relevant nullclines in (VRG, hNaPRG) space. The corresponding voltages of In - F and In - E are tracked in the lower boxes. For all neurons and V -nullclines, red indicates flexor and blue indicates extensor, the h-nullcline is shown in green, and the voltage threshold is indicated in magenta. (A) Feedback increases excitation to In - E, allowing it to reach threshold independently from RG - E. (B) In - E begins to inhibit RG - F, which raises the V -nullcline for RG - F (red). This change causes the voltage of In - F to decrease, yielding less inhibition to RG - E and thus lowering its V -nullcline (blue). (C) RG - E is now above the left knee of its V -nullcline, so it jumps to the right branch, crossing threshold and further exciting In - E as it does so. (D) RG - F falls below threshold after receiving full inhibition from In - E. Without excitation from RG - F, In - F falls below threshold as well.