Fig. 7.
Vm24 inhibition of DTH reactions in rats. Data are shown as differences in ear thickness between the ovalbumin-challenged left ear and the saline-treated right ear (mean ± S.E.M.). The treatment group of animals received a single dose of 0.1 mg/kg Vm24 administered subcutaneously at the time of the challenge, whereas the control group received the vehicle (PBS plus 2% rat serum). A, Vm24 inhibits active DTH directed against ovalbumin (n = 7 rats per group). **, p ≤ 0.01. B, Vm24 inhibits adoptive DTH induced with Kv1.3high-activated Ova-GFP T lymphocytes (n = 9 rats per group). *, p ≤ 0.05.