Table 1.
Phenotype and functional properties of pancreatic CSC populations.
| Study | Phenotype | Properties |
|---|---|---|
| Li et al.(5) | CD44+CD24+ESA+ | Increased Sonic Hedgehog expression. |
| Hermann et al.(7) | CD133+ | Chemoresistant. CD133+CXCR4+ cells responsible for metastasis. |
| Rasheed et al.(6) Ishizawa et al.(25) |
ALDH+ | CSCs associated with overall survival. CSCs exhibit mesenchymal feature and are frequently found in metastatic lesions. ALDH+ and CD44+CD24+ cells are equally tumorigenic. |
| Li et al.(22) | CD44+c-Met+ | Highly metastatic. |