. Author manuscript; available in PMC: 2013 Aug 15.

Published in final edited form as: Clin Cancer Res. 2012 Aug 15;18(16):4277–4284. doi: 10.1158/1078-0432.CCR-11-3112

Table 2.

Pancreatic CSC specific targeting strategies and agents

Study	Target receptor/pathway	Target population	Agent
Li et al.(22)	c-Met	c-Met^highCD44⁺ CD44⁺CD24⁺ESA⁺	XL184
Rajeshkumar et al.(51)	DR5	ALDH⁺ CD44⁺CD24⁺ESA⁺	DR5 Agonistic monoclonal antibody
Lonardo et al.(52)	ALK4	CD133⁺	SB431542
Jimeno et al.(11) Feldmann et al.(54) Feldmann et al.(53)	Hedgehog	ALDH⁺ CD44⁺CD24⁺ESA⁺	Cyclopamine, IPI269609
Mullendore et al.(57)	Notch	ALDH⁺	GSI-18
Zhang et al.(58)	EMT	CD133⁺	Salinomycin