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. Author manuscript; available in PMC: 2012 Aug 20.
Published in final edited form as: Nature. 2010 Mar 21;464(7290):852–857. doi: 10.1038/nature08851

Figure 5. Targeted deletion of the Sbds gene from osteoprogenitor cells recapitulates many features of the OCD fl/fl phenotype.

Figure 5

a, genetic model of Sbds deletion from osteoprogenitor cells b, leukopenia (n=8) c, dysplasia of neutrophils in peripheral blood d, dysplasia of megakaryocytes (micro-megakaryocytes) e, hypervascularity of the bone marrow f, increased intramedullary apoptosis of hematopoietic progenitor cells(n=5). Data are mean ± s.e.m. * p≤0.05, **p≤0.01.