Scheme 1.
Reagents and conditions: (a) i) Py·SO3, DMSO, Et3N, CH2CI2; ii) LiHMDS, EtOAc, −78 °C, THF; iii) TFA, CH2CI2; iv) Et3N, MeOH, reflux, 57% over four steps (b) LiAIH4, THF, 70%
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