. Author manuscript; available in PMC: 2013 Aug 9.

Published in final edited form as: J Med Chem. 2012 Jul 23;55(15):6751–6761. doi: 10.1021/jm3001218

Table 6.

Identification of genes affected by 13b

Pathway	Genes	P-Value
Development Hedgehog Signaling	Up-regulation: ubiquitin	5.423E-07
Development Hedgehog Signaling	Down-regulation: HSP90, SAP18, CDK11, β-catenin, Casein kinase I, Skp2/TrCP/FBXW, PKA-cat (cAMP-dependent), DYRK2	5.423E-07

Cell adhesion plasma signaling	Down-regulation: Fibronectin, PI3K cat. Class IA, XIAP, PLAU (UPA), FRS2, PI3K reg. class IA, Collagen IV	8.889E-06

Transport clathrin-coated vesicle cycle	Down-regulation: Myosin Vb, Rabaptin-5, Syntazin 7, PLEKHA8 (FAPP2), SNAP-25, Eps 15, VTI1B, EEA1, PECALM	2.284E-05