Table 1:
Patients' characteristics
| Variables | Group I (n = 24) | Group II (n = 26) | Group III (n = 27) | ANOVA P-value |
|---|---|---|---|---|
| Age (years) | 64 ± 13* | 72 ± 14 | 73 ± 10 | 0.04 |
| Male gender, n (%) | 18 (75) | 18 (69) | 15 (55) | 0.32 |
| Body mass index | 27.0 ± 3.6* | 26.0 ± 4.1 | 24.6 ± 3.0 | 0.05 |
| Comorbidities | ||||
| Hypertension, n (%) | 19 (79) | 18 (69) | 14 (52) | 0.10 |
| Diabetes, n (%) | 6 (25) | 6 (23) | 5 (18) | 0.85 |
| Arrythmia, n (%) | 3 (12) | 3 (11) | 6 (22) | 0.50 |
| Previous thromboembolic events | 2 (8) | 1 (4) | 1 (4) | 0.72 |
| Aspirin use | 12 (50) | 19 (73) | 14 (52) | 0.17 |
| Clopidogrel use | 5 (21) | 6 (23) | 7 (26) | 0.91 |
| Oral anticoagulants use | 3 (12) | 1 (4) | 4 (15) | 0.39 |
| Heparin use | 4 (17) | 5 (19) | 5 (18) | 0.88 |
| Type of procedure, n (%) | ||||
| CABG | 9 (38) | 9 (35) | 7 (26) | 0.4 |
| Valve | 13 (54) | 11 (42) | 13 (48) | |
| CABG + valve | 2 (8) | 6 (23) | 5 (19) | |
| Miscellaneous | 0 | 0 | 2 (7) | |
| No prior cardiac surgery | 24 (100) | 24 (92) | 26 (96) | 0.37 |
| Preoperative laboratory data | ||||
| Prothrombin time (%) | 95 ± 13 | 93 ± 18 | 91 ± 23 | 0.74 |
| aPTT (sec) | 32 ± 3 | 35 ± 6 | 34 ± 6 | 0.12 |
| Platelets (× 106/l) | 238 ± 79 | 211 ± 54 | 219 ± 68 | 0.35 |
| Fibrinogen (g/l) | 4.0 ± 1.1 | 4.2 ± 1.2 | 3.7 ± 1.2 | 0.35 |
| Haemoglobin (g/dl) | 14.2 ± 4.2 | 13.3 ± 1.4 | 13.4 ± 1.4 | 0.42 |
| EuroSCORE | 5.6 ± 2.7 | 6.7 ± 2.3 | 6.7 ± 2.5 | 0.20 |
| SAPS II | 28 ± 10 | 30 ± 10 | 34 ± 10 | 0.16 |
CABG: coronary artery bypass grafting; aPTT: activated partial thromboplastin time; SAPS II: simplified acute physiology score II.
*P = 0.05 group I vs group III.