Table 2:

Treatment and clinical course

Patient	Systemic administration		Period of arbekacin irrigation (days)			MRSA in PEc	Reop	Hospitalization (days)		Period of FU (months)
	Antibiotic	Duration (days)	Total	Low quantitya	Negativeb			After starting arbekacin irrigation	After removal of catheter
1	TEIC, arbekacin	33	16	7	9	None	No	22	6	44
2	TEIC, VCM	14	7	3	4	None	No	171	137	24
3	VCM, arbekacin	54	30	13	NA	Low	Yes	47	15	24
4	VCM	18	46	26	NA	Low	No	55	6	21
5	VCM	26	6	6	NA	Low	No	16	8	36
6	TEIC	17	16	2	9	None	No	34	13	6

MRSA: methicillin-resistant Staphylococcus aureus; PE: pleural effusion; Reop: reoperation; TEIC: teicoplanin; VCM: vancomycin; FU: follow-up; NA: not applicable.

^aPeriod until MRSA concentration in pleural effusion became low after starting arbekacin irrigation.

^bPeriod until MRSA concentration in pleural effusion became negative after starting arbekacin irrigation.

^cMRSA concentration in pleural effusion just before the removal of thoracic catheter.