Table 2.
Substrate-binding statuses in each subunit of Oxy in the catalytic cycle
| Statea |
Oxy subunits |
||
|---|---|---|---|
| Chain A | Chain B | Chain C | |
| (1) Resting (Oxy: Fdrest) |
- |
- |
- |
| (2) Reduced (Oxy: Fdred) |
- |
- |
- |
| (2’) CAR-bound (Oxy: FdCAR) |
- |
CAR |
CAR |
| (3) Reduced CAR-bound (Oxy: Fdred-CAR) |
- |
CAR |
CAR |
| (3’) Oxygen-bound (Oxy: FdO2) |
Peroxide (end-on) |
Peroxide (end-on) |
Peroxide (end-on) |
| (4) CAR- and oxygen-bound (Oxy: FdCAR-O2) |
Peroxide (end-on) |
Peroxide (side-on) |
Peroxide (side-on) |
| +CAR | +CAR | ||
a Numbers correspond to Figure 1.