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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Radiat Res. 2012 Jun 4;178(1):1–6. doi: 10.1667/rr2933.1

FIG. 2.

FIG. 2

Effects of pentoxifylline and α-tocopherol on ex vivo cardiac function measurements at 6 months after local heart irradiation. Panel A: The Langendorff ex vivo perfused heart preparation is commonly used for investigation of cardiac physiology and disease. The picture reflects a rat heart in a Langendorff apparatus. A left ventricular balloon is connected to a pressure transducer to obtain real-time pressures generated inside the left ventricle. Panel B: Treatment with pentoxifylline and α-tocopherol reduced left ventricular diastolic wall stress at 6 months after local heart irradiation with 5 daily fractions of 9 Gy. Data are shown as average ± SEM (n =6–8). *P < 0.05 irradiated compared to sham irradiation, #P < 0.05 pentoxifylline + α-tocopherol compared to vehicle. This figure presents data from (50).