TABLE 1.
Patient Demographics
| Parameter | Asthma (n = 88) | Non-asthma (n = 29) | P-value |
|---|---|---|---|
| Age mean (SD) | 7.7 (3.6) | 7.3 (4.2) | 0.7091 |
| Male gender, n (%) | 50 (58.8%) | 16 (59.3%) | 1.0000 |
| Height (cm) | 126.4 (19.9) | 126.8 (25.5) | 0.9480 |
| Weight (kg) | 33.9 (27.2) | 30.4 (16.9) | 0.4311 |
| Ethic origin | |||
| Caucasian | 46 (56.1%) | 16 (61.5%) | 0.6566 |
| Black | 16 (19.2%) | 6(23.1%) | 0.7809 |
| Hispanic | 6 (7.3%) | 0 (0.0%) | 0.3322 |
| Asian | 14(17.1%) | 4 (15.4%) | 1.0000 |
| Atopy (%) | 75 (89.3%) | 24 (88.9%) | 1.0000 |
| Total IgE, IU/ml (SD) | 1430.9 (3519.3) | 1090.1 (4149.0) | 0.7090 |
| Tryptase (ng/ml) | 3.6 (1.8) | 3.8 (1.4) | 0.5716 |
| Asthma based on parent assessment (%) | 67 (77.9%) | 1 (3.7%) | 0.0001 |
| Use of Monteleukast | 18 (20.5%) | 0 (0.0%) | 0.0060 |
| Use of inhaled corticosteroids | 32 (36.4%) | 0 (0.0%) | 0.0001 |
| Baseline measurements | |||
| R5 (cmH2O/L/sec) | 102.8 (23.8) | 105.2 (21.7) | 0.6274 |
| R10 (cmH2O/L/sec) | 95.3 (21.6) | 102.1 (15.9) | 0.0898 |
| R20 (cmH2O/L/sec) | 95.2 (21.9) | 98.2 (17.3) | 0.4809 |
| R5-R20 (cmH2O/L/sec) | 29.0 (10.6) | 30.1 (11.4) | 0.6536 |
| X5 (cmH2O/L/sec) | 108.7 (49.7) | 127.1 (75.2) | 0.2483 |
| AX (cmH2O/L) | 115.4 (71.2) | 132.0 (48.7) | 0.2399 |
| Bronchodilator response | |||
| ΔR5 (%) | –16.0(11.1) | –9.0 (12.0) | 0.0082* |
| ΔR10(%) | –15.5 (9.7) | –8.0 (9.9) | 0.0008* |
| ΔR20(%) | –9.3 (11.7) | –5.9 (11.9) | 0.2079 |
| ΔR5–R20 (%) | 23.8 (10.2) | 27.6 (10.7) | 0.1024 |
| ΔX5 (%) | –17.4 (23.7) | –6.8 (21.0) | 0.0269* |
| ΔAX (%) | –38.4 (20.5) | –19.7 (25.5) | 0.0009* |
*
P < 0.05.