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End-plate current (EPC) 90–10% decay time is prolonged for EDL muscles removed from diabetic mice. A: representative EPCs recorded for control as well as mice having 2 or 4 wk of STZ-induced hyperglycemia. B: EPC 90–10% decay time is significantly (***P < 0.01) greater than control at 2 and 4 wk after the onset of STZ-induced hyperglycemia. Bars represent the mean + SE obtained from 4 to 5 EDL fibers of 4 mice (10–11 EPCs/fiber).
