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. 2012 May 16;303(4):F559–F568. doi: 10.1152/ajprenal.00615.2011

Fig. 5.

Fig. 5.

Apamin increases the spontaneous phasic contraction amplitude, muscle force integral, phasic contraction duration, and muscle tone in human DSM isolated strips. A: original DSM tension recordings illustrating apamin (1 μM) effect on human DSM isolated strips. B: summary data showing significant increase in human DSM spontaneous phasic contractions amplitude, muscle force integral, and muscle tone within 10 min following apamin (1 μM) addition. C: summary data showing a significant increase in human DSM spontaneous phasic contractions amplitude, muscle force integral, and phasic contraction duration 30–40 min following apamin (1 μM) addition. The 10-min control period before apamin addition was taken to be 100% and data were normalized. Values are means ± SE (n = 28, N = 13; **P < 0.01, ***P < 0.005). Tetrodotoxin (TTX; 1 μM) was present throughout the experiments.