Table 1.
Hemodynamic and limb vascular responses to 8 wk of fish oil or placebo in normotensive humans
| Fish Oil (n = 19) |
Placebo (n = 19) |
|||||
|---|---|---|---|---|---|---|
| Variable | Pre | Post | Pre | Post | Time | Time × Drug Interaction |
| Sex (male/female) | 9/10 | – | 9/10 | – | – | – |
| Age, yr | 24 ± 2 | – | 24 ± 2 | – | – | – |
| Height, cm | 170 ± 2 | – | 170 ± 2 | – | – | – |
| Body mass, kg | 68 ± 3 | 69 ± 3 | 70 ± 2 | 71 ± 2 | 0.17 | 0.92 |
| BMI, kg/m2 | 24 ± 1 | 24 ± 1 | 24 ± 1 | 24 ± 1 | 0.85 | 0.53 |
| SAP, mmHg | 110 ± 1 | 107 ± 1 | 107 ± 2 | 107 ± 2 | 0.19 | 0.17 |
| DAP, mmHg | 66 ± 1 | 66 ± 1 | 65 ± 1 | 66 ± 1 | 0.28 | 0.69 |
| MAP, mmHg | 80 ± 1 | 80 ± 1 | 79 ± 1 | 80 ± 1 | 0.78 | 0.42 |
| HR, beats/min | 71 ± 2 | 71 ± 2 | 74 ± 2 | 76 ± 2 | 0.46 | 0.43 |
| RRI, ms | 931 ± 59 | 985 ± 35 | 971 ± 29 | 910 ± 23 | 0.90 | 0.05 |
| RRISD, ms | 66 ± 4 | 77 ± 7* | 81 ± 7 | 69 ± 6 | 0.89 | 0.02 |
| FBF, ml·100 ml tissue−1·min−1 | 2.5 ± 0 | 2.8 ± 0 | 2.2 ± 0 | 2.5 ± 0 | 0.05 | 0.81 |
| FVC, 100 * ml·100 ml tissue−1· min−1·mmHg−1 | 3.1 ± 0 | 3.5 ± 0 | 2.8 ± 0 | 3.0 ± 0 | 0.06 | 0.59 |
| CBF, ml·100 ml tissue−1·min−1 | 2.0 ± 0 | 2.2 ± 0 | 2.2 ± 0 | 2.3 ± 0 | 0.14 | 0.70 |
| CVC, 100 * ml·100 ml tissue−1·min−1·mmHg−1 | 2.4 ± 0 | 2.8 ± 0 | 2.8 ± 0 | 2.9 ± 0 | 0.17 | 0.47 |
Values are means ± SE.
BMI, body mass index; SAP, systolic arterial pressure; DAP, diastolic arterial pressure; MAP, mean arterial pressure; HR, heart rate; FBF, forearm blood; FVC, forearm vascular conductance; CBF, calf blood flow; CVC, calf vascular conductance.
Forearm vascular measurements: n = 18 fish oil and n = 18 placebo; calf vascular measurements: n = 16 fish oil and n = 16 placebo.
*
Significantly different from corresponding Pre value (P < 0.05, post hoc analysis).