Table 2.

Calcium transients and contractility parameters of cardiomyocytes isolated from control or Akita mice

	Calcium Transient		Sarcomeric Shortening
	Control	AkitaIns2	Control	AkitaIns2
Baseline	1.74 ± 0.05	1.73 ± 0.02	1.54 ± 0.06	1.57 ± 0.05
Peak height	0.11 ± 0.01	0.11 ± 0.01	0.15 ± 0.02	0.13 ± 0.01
Time to peak, ms
10%	36.0 ± 1.6	41.5 ± 3.0*	16.68 ± 0.02	18.05 ± 0.06*
50%	63.9 ± 1.3	73.7 ± 4.1*	35.06 ± 0.04	37.17 ± 0.07*
90%	96.1 ± 5.0	110.7 ± 6.4*	58.41 ± 0.18	60.61 ± 0.11
Time to baseline, ms
10%	145.2 ± 5.1	178.8 ± 9.5*	113.5 ± 3.6	126.7 ± 6.7*
50%	178.9 ± 3.8	225.7 ± 6.0*	188.1 ± 0.5	233.9 ± 2.8*
90%	244.1 ± 20.4	357.8 ± 29.4*	378.5 ± 23.3	508.5 ± 39.6*

Values are means ± SD.

^*P < 0.05.